Best practices for selection of excipients for paediatrics – Workshop reflection
نویسندگان
چکیده
The development of age appropriate formulations for the paediatric population has become one key areas focus pharmaceutical industry - with a subsequent influence on excipient use. Selection excipients safety and tolerability is major hurdle in formulation development. Various factors selection excipients, including target group, route administration dosage form. Evaluation these clear rationale justification expected by regulators when it comes to selecting formulation. Scientists are encouraged apply principle benefit risk balance assess suitability specific whom intended. In order understand how scientists approach task establishing analysis, workshop was organised European Paediatric Formulation Initiative (EuPFI) reflect current scenario different practices employed formulations. Aspects assessed were also canvassed. Finally, participants asked comment use may differ from considerations applied other groups. Based discussion, some recommendations questions consider emerged regarding drug These best practice provided good starting point more systematic strategy
منابع مشابه
the test for adverse selection in life insurance market: the case of mellat insurance company
انتخاب نامساعد یکی از مشکلات اساسی در صنعت بیمه است. که ابتدا در سال 1960، توسط روتشیلد واستیگلیتز مورد بحث ومطالعه قرار گرفت ازآن موقع تاکنون بسیاری از پژوهشگران مدل های مختلفی را برای تجزیه و تحلیل تقاضا برای صنعت بیمه عمر که تماما ناشی از عدم قطعیت در این صنعت میباشد انجام داده اند .وهدف از آن پیدا کردن شرایطی است که تحت آن شرایط انتخاب یا کنار گذاشتن یک بیمه گزار به نفع و یا زیان شرکت بیمه ...
15 صفحه اولBest Practices for Intrathecal Baclofen Therapy: Patient Selection.
INTRODUCTION When spasticity interferes with comfort, function, activities of daily living, mobility, positioning, or caregiver assistance, patients should be considered for intrathecal baclofen (ITB) therapy. METHODS An expert panel consulted on best practices. RESULTS ITB can be considered for problematic spasticity involving muscles/muscle groups during all phases of diseases, including ...
متن کاملBest Practices in Treatment Selection for Patients With Advanced NSCLC.
Worldwide, lung cancer is the most prevalent form of cancer, and its non-small-cell subtype constitutes up to 85% of cases. Overall, lung cancer is the most common cause of cancer-related death in the United States for both sexes, and its 5-year survival rate is 17%. It is a heterogeneous disease characterized by a variety of biomarkers and differing histologies. Non-small-cell lung cancer may ...
متن کاملAre Java Programming Best Practices Also Best Practices for Android?
1998 CR Categories: D.1.5 [Programming Techniques] Object-oriented Programming; D.2.2 [Software Engineering] Design Tools and Techniquesobject-oriented design methods; D.2.3 [Software Engineering] Coding Tools and Techniquesobject-oriented programming; D.3.3 [Software Engineering] Language Constructs and Featuresclasses and objects, dynamic storage management; D.4 [Operating Systems] Storage...
متن کاملCHARGED SYSTEM SEARCH FOR OPTIMUM DESIGN OF COST-EFFECTIVE STRUCTURAL BEST MANAGEMENT PRACTICES FOR IMPROVING WATER QUALITY
Best Management Practices (BMPs) are implemented in a watershed to reduce the amount of non-point source pollutants transported to water bodies. However, an optimization algorithm is required to choose the efficient type, size, and location of BMPs for application in a watershed for improving the water quality. In this study, the Charged System Search, a well-known and powerful meta-heuristic o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Pharmaceutics and Biopharmaceutics
سال: 2021
ISSN: ['0939-6411', '1873-3441']
DOI: https://doi.org/10.1016/j.ejpb.2020.12.021